There are no specific antiviral medicines for dengue. Treatment of acute dengue is supportive, using either oral or intravenous rehydration for mild or moderate disease, and intravenous fluids and blood transfusion for more severe cases.

There are not yet any vaccines to prevent infection with dengue virus.

Maintenance of the patient's circulating fluid volume is the central feature of dengue hemorrhagic fever (DHF) care.

Paracetamol is recommended to easy the fever and pain symptoms. Aspirin is not used because it can affect blood clotting.