Body - with nodules subcutaneous Fatigue/exhaustion   Fever
Joints - pain Joints - swelling Joints - tender to the touch
Joints - stiffness Muscles - aching Weight - loss
Rheumatoid arthritis is an autoimmune disease that may affect many tissues and organs, but principally attacks synovial joints. The arthritis of joints (synovitis) is the inflammation of the synovial membrane that lines joints and tendon sheaths. Rheumatoid arthritis can affect any joint but is common in the wrist and fingers. Rheumatoid arthritis can also produce diffuse inflammation in the lungs, pericardium, pleura, and sclera. Also, nodular lesions, most common in subcutaneous tissue under the skin and located near the elbow, although they can appear anywhere.

Although rheumatoid arthritis can have many different symptoms, joints are always affected. It is still unknown what starts this process. Because it is a chronic disease, rheumatoid arthritis continues indefinitely and may not go away. Frequent flares in disease activity can occur.
Rheumatoid arthritis can be difficult to diagnose. No blood test can definitively confirme the diagnosis. Likewise, X-ray may not show abnormalities for months after the joint pain started. However, the following tests can show indications that the condition is developing:

- Blood test for rheumatoid factor.

- Blood test for C-reactive protein.

- Blood test for erythrocyte sedimentation rate (ESR test).

- Complete blood count.

- X-ray (several months after the onset of joint pain).
  More information:
Rheumatoid Arthritis Treatment
Rheumatoid Arthritis Healthcare Centers

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